Acceptance rules
The food additive potassium citrate should be inspected by the technical department of the production plant. The manufacturer shall ensure that all products manufactured meet the requirements of this standard, and each batch of products shall be accompanied by a quality certificate, including: manufacturer name, product name, batch number, date of manufacture, net weight, serial number of this standard, etc.
The user has the right to check and accept the quality of the products received in accordance with the provisions of this standard, and whether the result meets the requirements of this standard.
The weight of each batch does not exceed 2t.
Sampling shall be carried out according to Article 6.6 of GB6678 and Article 2.3.1 of GB6679. The total amount of sampling should not be less than 500g. It should be fully mixed and stored in two clean, dry and airtight containers. Labels should be attached to indicate the name of the manufacturer, product name, batch number, and date. One is for inspection and one is reserved for future reference. The retention period is half a year.
If any of the inspection results does not meet the requirements of this standard, a sample shall be taken from the double-volume package for re-inspection. Even if the result of the re-inspection only has one item that does not meet the requirements of the standard, the entire batch of products is unqualified.
When there is an objection between the supplier and the buyer on the quality of the product, it shall be dealt with in accordance with the provisions of the "Interim Measures for the National Product Quality Arbitration and Inspection".
Folding packaging signs, transportation and storage
Sign
There should be a firm and clear mark on the packaging bag, and the name of the manufacturer, address, product name, trademark, number of this standard, batch number, production date, net weight and the words "food additives" should be written.
Package
The food additive potassium citrate is packed with food-grade polyethylene film and double-layer kraft paper or double-layer food-grade polyethylene film bag for inner packaging, and plastic woven bag for outer packaging. The net weight of each bag is 25kg, and the allowable error of the filling volume is ±0.5%, and it can also be packaged according to user needs.
Transport and storage
During transportation, the packaging should be kept intact, waterproof and moisture-proof. Mixed transportation and storage with toxic substances is strictly prohibited, and should be stored in a cool, dry and ventilated place.
This product has a storage period of one and a half years under the storage and transportation conditions specified in this standard from the date of delivery.
Potassium citrate is an oral supplement that is used daily to alkalinize urine and dissolve calcium in the urine. It can theoretically reduce the risk of kidney stones. A recent study by Dr. Melanie A. McNally of the Johns Hopkins University School of Medicine in Baltimore, Maryland, pointed out that about 6% of children receiving a ketogenic diet have kidney stones.
The sample of this study included 313 children who met the indications for daily use of potassium citrate. They started on the ketogenic diet at Johns Hopkins Hospital between 2000 and 2008, and each child was followed up for at least one month. Between 2000 and 2005, children who received high urinary calcium on a ketogenic diet received a dose of 2 mEq per kilogram per day. Since 2006, all children on the ketogenic diet have used potassium citrate empirically.
4 out of 198 children who used potassium citrate for prevention (2.0%), and 11 out of 105 children who did not use potassium citrate (10.5%) developed kidney stones (P=0.003). Beginning in 2006, 2 children refused to supplement potassium citrate; 1 of these 2 children developed kidney stones. At the beginning of the ketogenic diet, children who successfully received prophylactic potassium citrate had a kidney stone incidence of 0.9% (1/106), and children who received potassium citrate because of high urine calcium were 6.7% (13/ 195).
Although the urine of children who received potassium citrate was relatively alkaline (average pH was 6.8 vs. 6.2; P=0.002), the blood pH of this group did not decrease. Potassium citrate is well tolerated and has no significant side effects.
The study authors wrote that oral potassium citrate is an effective supplement to prevent kidney stones for children on a ketogenic diet. It can achieve the goal of alkalizing urine and is worthy of a comprehensive supplement.
But this study lacks randomization.
The authors of the study concluded that we recommend that when starting a ketogenic diet, educate about the importance of regular potassium citrate supplementation, and then emphasize its importance at every visit. More research will help determine whether high-dose potassium citrate can be completely prevented or can be used in combination with other supplements, such as compound vitamins, to increase compliance.
Main purpose of this paragraph
In the food industry, it is used as buffer, chelating agent, stabilizer, antioxidant, emulsifier, flavoring agent, etc. It can be used in milk and dairy products, jelly, jam, meat, canned hydrogel desserts, cheese emulsification, citrus preservation, etc.; in the pharmaceutical industry for hypokalemia and potassium deficiency and alkalization of urine. It can also be made into high-efficiency compound fertilizers, and can also be used in papermaking, gilding and other industries.
Drugs to prevent urinary stones
Potassium citrate is currently the most commonly used medicine to prevent stones. Studies have found that the pH and citric acid values in the urine are closely related to the formation of urinary stones. In acidic urine (pH<5.5), the solubility of uric acid is extremely low, which is easy to cause uric acid stones; while in alkaline urine (pH>7), calcium phosphate or magnesium phosphate stones are easily formed. 63% of patients with urinary calculi have lower than normal urinary citric acid, and potassium citrate can provide a large amount of citric acid to increase the pH value in urine, so for uric acid stones, hypocalcium citrate stones and renal tubular poisoning The calcium stone disease caused by it has a very significant therapeutic effect. But this will increase the potassium ions in the urine and decrease the ammonia ions. This is because potassium citrate not only supplements citric acid, but also supplements potassium. Due to the rapid metabolism of potassium in the body, there is no change in the potassium content in the blood, so it has little effect on the body. From the daily total urine output, oxalic acid, phosphate, sodium, magnesium, sulfate and uric acid of patients with uric acid stones, it was found that it was not affected by taking potassium citrate
